Esculapio follows a double-blind peer review policy to enhance the quality of published literature. After initial assessment of the submitted manuscript by the editor, if the manuscript is found deficient, the author is informed and asked to fulfil the requirements within a week’s time and if approved by the editor then it is sent for peer review by external peer reviewer. Journal maintains a reviewers database according to their subject specialty as identified by the Editorial board. An average of two week’s time is given to reviewers for reviewing the manuscript. A single manuscript is sent to one reviewer at a time.  

Esculapio encourages its reviewers to follow COPE guidelines for peer reviewer.  The article reviewed is sent back to author if corrections are advised after peer review.  In case article is rejected by the reviewer, it is sent to another reviewer along with the comments from the initial reviewer. Final decision for the paper acceptance or rejection lies with the editor after reviewing the comments and the reviewers are informed about the final decision.