Comparison of Intrathecal Dexmedetomedine with Dexamethasone as Adjuvant to Bupivacaine in Caesarian Section: A Double Blind Study

Naila Asad; M. Azam; Asma Samreen; Ali Rehman; Usman Jahangir

doi:10.51273/esc23.251319413

Authors

Naila Asad SIMS
M. Azam
Asma Samreen
Ali Rehman
Usman Jahangir

DOI:

https://doi.org/10.51273/esc23.251319413

Keywords:

Dexmedetomedine, Dexamethasone,, Caesarian Section, Spinal Anaesthesia

Abstract

Objective: To compare the effects of dexmedetomidine versus dexamethasone as intrathecal additives in elective LSCS.
Material and Method: Sixty parturients at term aged 18-40 years, were included in this study. Spinal anaesthesia was administered to all for caesarian section. 0.5% hyperbaric bupivacaine (10mg) was given to all patients. D group (n=30) was given dexamethasone 6mg as adjuvant. Dexmedetomedine (0.5 ml) 5μg was added in Group BD. Similar syringes were used for drugs to ensure blinding. Haemodynamic changes were measured. Pinprick method was used to assess the onset and duration of sensory block. Time to two segment sensory regression was documented. Modified Bromage scale assessed the onset and duration of motor block.
Results: The mean sensory block onset time was earlier with dexamethasone than Dexmedetomedine. Duration of analgesia and two segment sensory regression time and duration of motor block was significantly longer with dexmedetomidine (Table:2 & 3). Significant decrease in systolic and diastolic blood pressure was seen from baseline till uterine incision in both groups (Fig:B & C). Incidence of postoperative shivering, nausea and vomiting were significantly reduced with dexmedetomidine (Fig: D & E).
Conclusion: Dexmedetomidine is superior to dexamethasone in providing better sensory and motor block along with prolonged analgesia duration.

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