Comparison of Efficacy of Cryotherapy Versus Intralesional Vitamin D3 in the Treatment Of Plantar Warts

Abstract

Objective: To compare the efficacy of cryotherapy versus intralesional vitamin D3 in plantar warts.
Method: A Randomized controlled trial conducted from 30th July 2020 -29th January 2021 in the
Department of Dermatology, Services Hospital, Lahore. 110 patients of both genders with age ranging from
18-60 years suffering from plantar warts (for more than 4 weeks) participated. Those allergic to xylocaine and
Vitamin D3, pregnant females, immunocompromised, having bleeding disorders, Raynaud's phenomenon or
cold urticaria were excluded. Participants were randomly divided in two groups. Group A patients was treated
with cryotherapy and Group B was treated with intralesional Vitamin D3 for 4 sessions 2 weeks apart.
Patients were followed at each treatment session every 2 weekly and then in OPD every month for 4 months
for treatment response. Efficacy was assessed as complete cure of the lesion.
Results: Mean age of patients in group A was 34.36 ±12.06 years and in group B was 31.93 ±10.99 years
with 81 (73.64%) patients between 18 to 40 years. Male patients were 76 (69.09%) and 34 (30.91%) were
females. Efficacy of Group A was 56.36% while Group B showed 87.27% (p-value = 0.0001).
Conclusion: This study concluded that intralesional vitamin D3 is more effective than cryotherapy in the
treatment of plantar warts.

How to cite: Aslam H, Siddiqui S, Cheema A, Aman S, Dastgeer S, Ehasn H. Comparison of Efficacy of Cryotherapy Versus
Intralesional Vitamin D3 in the Treatment Of Plantar Warts. Esculapio - JSIMS 2022;18(02):174-178
DOI: https://doi.org/10.51273/esc22.2518214