Metabolic Syndrome and Hyperandrogenemia in Polysystic Ovarian Syndrome

Abstract

Objective: To ascertain the frequency of hyperandrogenemia in cases of polycystic ovarian syndrome and to
correlate the frequency of metabolic syndrome in polycystic ovarian syndrome patients with and without
hyperandrogenemia.
Method: This cross sectional study was conducted from 19.12.2020 to 18.06.2021 in Department of
Obstetrics & gynecology, Unit-II, Aziz Bhatti Shaheed Teaching Hospital, Gujrat. Data was collected from a
consecutive sample of 367 women diagnosed of polycystic ovarian syndrome(PCOS). All the female patients
aged between 18-35 years diagnosed of PCOS included in the study except pregnant or lactating females.
Results: The mean age was calculated as 26.35 (± 5.28) years. Presence of hyperandrogenemia was found in
59.9% patients. In 220 hyperandrogenemic patients, the metabolic syndrome was present in 20% while
metabolic syndrome was present in 10.20% patients without hyperandrogenemia. Significant higher
occurrence of metabolic syndrome was found in hyperandrogenemia group as compared to without
hyperandrogenemia group (20% VS 10.2%) having p-value = 0.014. Stratified age have significant
relationship for the presence of hyperandrogenemia with p-value=0.000. Body mass index and duration of
illness didn't show significant relationship having p-value > 0.05. Duration of illness was positively
associated with presence of metabolic syndrome having p-value = 0.014.
Conclusion: Significant higher occurrence of metabolic syndrome was found in hyperandrogenemia group
as compared to those without hyperandrogenemia in PCOS patients.

How to cite: Hummayun H, Naz T, Waheed SS. Metabolic Syndrome and Hyperandrogenemia in Polysystic Ovarian
Syndrome. Esculapio - JSIMS 2022;18(02):169-173
DOI: https://doi.org/10.51273/esc22.2518213