Serum Magnesium in Patients of Type 2 Diabetes Mellitus

Abstract

Objective: Magnesium has a role in glucose homeostasis and insulin sensitivity in patients of
diabetes mellitus. This study was conducted to compare the levels of serum magnesium in type-2
diabetic patients (controlled and uncontrolled) with non-diabetic controls.
Material and Methods: This cross-sectional comparative study was carried out in eighty patients
with type-2 diabetes and forty healthy, age and sex matched controls. Diabetic patients were
selected after taking detailed history from the outpatient Diabetic Clinic of Services Hospital,
Lahore. They were analyzed for serum magnesium, fasting blood glucose and glycosylated
hemoglobin (HbA1c) levels.
Results: Mean±SD serum magnesium levels of the type 2 diabetic uncontrolled cases were
significantly lower (p<0.01) than in the non-diabetic control subjects (0.771±0.208 mmol/l and
0.901±0.128 mmol/l). These levels were non-significantly lower in controlled diabetic patients.
There was inverse correlation (r = - 0.084) between the serum magnesium with fasting blood
glucose and glycosylated hemoglobin in the type 2 controlled diabetic patients.
Conclusion: Hypomagnesemia is present in type 2 diabetic patients.