Association between Antiphospholipid Antibodies (APLA) and Preeclampsia (PE) in Females Presenting for Antenatal Check-up

Abstract

Objective: To assess the association between antiphospholipid antibodies (APLA) and preeclampsia (PE) in
females presenting for antenatal check-up.
Method: After ethical committee approval and informed consent 200 obstetric patients fulfilling inclusion
criteria were included in this case control study from OPD of unit 2 Obstetrics and Gynecology Department
of Lady Willingdon Hospital Lahore. Demographic record was maintained and two groups were created, case
and control on the presence or absence of PE
Results: mean age of case group was 27.60±4.96 ranging from 20 to 35 years while mean age of control
group was 27.94±4.13 also ranging from 20 to 35 years Mean gestational age of case group was27.46± 4.72
weeks ranging 20 to 35 weeks while mean gestational age of control group was 27.25± 4.74 weeks, ranging
20 to 35 weeks. There was significant association between preeclampsia and APLA as the p-value was
significant (p-value=0.007).
Conclusion: Results of this study showed a significant association and significant risk between APLA and
preeclampsia. obstetric patients with a high risk of preeclampsia, must have routine APLA assay.in women
with early onset pre-eclampsia APLA should routinely be tested. When other clinical features are suggestive
of APs.

How to cite: Mubeen S, Janjua M, Iftikhar A, Akmal M, Parveen S, Hussain M. Association between Antiphospholipid Antibodies
(APLA) and Preeclampsia (PE) in Females Presenting for Antenatal Check-up. Esculapio - JSIMS 2022;18(02):148-151
DOI: https://doi.org/10.51273/esc22.251829