Frequency Of Restrictive Pulmonary Dysfunction In Type-1 & Type-2 Diabetes Mellitus

Abstract

Objective: To determine the frequency of restrictive pulmonary dysfunction in type 1 & type 2
diabetic patients and to measure the severity of pulmonary dysfunction.
Material & Methods: This study included 255 patients of type I and type II diabetes who had
followed up in the out patient departments of Pulmonology and Medicine in Mayo Hospital,
Lahore. Forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1) were
measured using standard spirometry.
Results: Mean age was 47.26±19.076 years. 230 (90.2%) were males and 25 (9.8%) were
females. 58 (22.7%) were type 1 diabetics and 197 (77.3%) were type 2 diabetics. 37 (14.5%) had
restrictive pathology, 6 (2.4%) had obstructive pathology and 212 (83.1%) had normal lung
function tests. 35 (13.7%) had mild restrictive dysfunction and 2 (0.8%) had moderate restrictive
lung dysfunction.
Conclusion: These data support the notion that the lung is a target organ for diabetic injury.
Additional research is required to identify pathophysiologic mechanisms and to determine clinical
significance