Single Dose Methotrexate in Ectopic Pregnancy

Abstract

Objective: To evaluate the efficacy of a single dose of MTX for ectopic pregnancy management.
Material and Methods: 37 patients were carefully selected according to inclusion criteria. β-hCG
was done at diagnosis and at day 7. A single IM dose of MTX was given & patients were kept
admitted till recovery.
Results: Out of the 37 patients, 5 patients had ruptured ectopic pregnancy in spite of taking MTX.
26 had single dose and had a time of ectopic pregnancy resolution averaging 26.4 days. The
remaining 6 patients received an additional dose of MTX with the time resolution of 35 days.
Conclusion: The successful medical management of ectopic pregnancy was seen in 26 patients
(81%) in whom β-hCG levels became negative after administration of single MTX.