To Study the Role of Serum Biliurbin and Lipoproteins in Prediction of Ischemic Heart Disease

Abstract

Objective: To determine if serum bilirubin, when combined with various risk factors like lipid and
lipoprotein predicts ischemic heart disease (IHD).
Material & Methods: Hundred patients with IHD were included in the study from in and out
patient departments of Medicine. 25 normal subjects were studied as controls. The traditional risk
factors like cholesterol, high-density lipoprotein cholesterol (HDL-C), cholesterol/HDL-C ratios,
triglycerides as well as serum bilirubin, albumin and creatinine were determined by standard
methods. Besides, age, cigarette smoking, and systolic blood pressure were also recorded.
Results: It was observed that the bilirubin is negatively correlated with hemoglobin, albumin,
HDL and LDL-cholesterol. On the other hand a direct correlation with total lipid, cholesterol and
ratio of cholesterol/HDL-cholesterol is also observed. High level of serum creatinine level was
also found in the patients as compared to normal subjects.
Conclusion: No definite relationship between serum bilirubin and IHD was observed.