Frequency of Dementia in Patients with Parkinson’s Disease in a Tertiary Care Hospital in Lahore

Abstract

Objective: The objective of the study is to determine the frequency of dementia in patients with
Parkinson's disease.
Material and Methods: A hundred patients of Parkinson's disease presenting to OPD between
the ages of 40 and 100 years were enrolled in the study and dementia was assessed in these
patients by performing mini-mental state examination .
Results: Mean age was 69.31±16.37years,. The age range was 40-100 years, but 68 (68 %)
patients were more than 60 years of age. Out of the 100 patients, 66 (66%) were males and 34 (34
%) were females. Mean mini-mental state score at admission was 16.75±2, 7(24%) Patients
were having mini-mental score of 5-10 , 10 patients (34%) had mini-mental score 11-18, and 12
patients (41%) had mini-mental score of 19-24 at presentation. Mean duration of disease was
11±2.08 years. Out of total 100 patients, 29 (29%) patients had dementia ,whereas 71 (71%) did
not have cognitive impairment.
Conclusion: It is concluded from the study that dementia develops in considerable number of
patients and is most commonly associated with late onset of disease and with longer duration of
PD. Most of the patients had moderate dementia. Therefore, it is recommended that every patient
with PD should be assessed for cognitive impairment so as to enable early detection of dementia
and to halt the progression in such patients