Comparision Of Hemodynamic Changes Caused By 2 Units Versus 5 Units Of Oxytocin During Elective Caesarian Section Under Spinal Anaesthesia

Abstract

Objective: To compare the effects of 2 units and 5 units bolus doses of oxytocin on heart rate
and mean arterial pressure during elective caesarian section under spinal anaesthesia.
Material and Methods: Randomized control study ,conducted over 6 months period on 150
patients at Maula Baksh Teaching Hospital Sargodha by dividing into 2 groups(group A & group
B),through lottery method for randomization of oxytocin allocation.
Results: In our study, majority of the patients i.e. 45.33%(n=34) in Group-A and 38.67%(n=29) in
Group-B were between 26-30 years of age, mean ± SD was calculated as 27.85±3.54
years.,while 60%(n=45) in group A and 56%(n=42) in group B were between 37-39 wks of
gestation ,mean ± SD was calculated as 38.63±4.61wks.Blood loss in both groups shows
insignificant difference by recording 187.43±18.65 ml in Group-A and 194.24±21.47 ml in Group-
B, comparison of tachycardia in both groups was done which shows 32%(n=24) in Group-A and
61.33%(n=46) in Group-B while which shows a significant difference in both groups while
hypotension was recorded as 4%(n=3) in Group-A and 17.33%(n=13) in Group-B, p value was
calculated as <0.01.
Conclusion: We concluded that frequency of tachycardia and hypotension in patients
administered with 2 IU bolus dose of oxytocin is significantly lesser as compared to 5IU bolus
dose and there is no difference in the incidence of postpartum haemorrhage