Encountering Xanthogranulomatous Inflammation in a Myriad of Settings

Abstract

Xanthogranulomatous inflammation is a rare but well recognized variety of
chronic inflammation seen in multiple sites. It may present as a mass lesion and mimic malignant
tumors, in other cases it may be discovered as an incidental finding in tissues removed for
different reasons. Xanthogranulomatous inflammation was encountered in five different cases
which included two gall bladders, one kidney, one endoscopic biopsy from gastric mucosa and
one collaural fistula. The demographic data as well as pathological findings are described. After
Although the exact etiopathogenesis of xanthogranulomatous inflammation is still debated, it is
agreed that it has no pre-malignant potential. Therefore, resection is considered adequate
therapy for effected patients. This makes it all the more important to recognize it in its various
morphological forms, even in endoscopic biopsies, to avoid unnecessary extirpative procedures.