Comparison of Apoptotic Effect of Withania Coagulans in Hela1, Viro and BHK Cancer Cell Lines

Abstract

Objectives: Cancer is the second leading cause of death and has a complex etiology. Efforts are
being made to target different components for its treatment. Developments in the field of
molecular biology have led the researchers to target apoptotic pathway. This study has been
designed to assess the apoptotic effect of the extract of withaniacoagulans on different cancer cell
lines.
Methodology: This study was designed to check the anticancer activity of withaniacoagulans
and to compare it in different cancer cell lines.
Results: The extract of withaniacoagulans proved to be equally effective in hela, vero and bhk
cell lines even at concentration of 10μg/ml.
Conclusions: The extract has a potential to act as apoptotic compound. Study can be
elaborated by isolating different components and assessing their role as apoptotic molecules on
individual basis.