Prevalence of Comorbidities Linked to Integrated Management of Childhood Illness Among Children with Diarrhea
DOI:
https://doi.org/10.51273/esc25.251321111Keywords:
paediatric acute diarrhea, infection, malnutrition in children, nutritional rickets, Diarrhea,Abstract
Abstract
Objective: This study aims to assess the prevalence of various comorbidities related to the Integrated
Management of Childhood Illness (IMCI) among children presenting with diarrhea.
Material and Methods: A descriptive cross-sectional study was conducted at the Department of Pediatrics,
Services Hospital Lahore (Ref No. IRB/2024/1410/SIMS dated 22.08.2024). A total of 383 children aged 1-5
years who presented with diarrhea were included using a non-probability consecutive sampling method.
Diarrhea was defined as the passage of three or more loose stools per day. The prevalence of IMCI-related
comorbidities including malnutrition, anemia, rickets, ear infections, and worm infestations was assessed
through clinical evaluation and laboratory tests. Data on demographic characteristics, breastfeeding and
weaning practices, vaccination status, and medical history were collected. Chi-square tests were used to
determine associations between comorbidities and diarrhea prevalence, with significance set at p ≤ 0.05.
Results: The study revealed a high prevalence of malnutrition (54.6%), anemia (55.9%), and rickets (30.8%)
among the children with diarrhea. Significant associations were observed between malnutrition, anemia, and
rickets (p < 0.001) with diarrhea prevalence. Ear infections were less common (4.17%) but still showed a
significant association (p = 0.049). Worm infestations, however, did not show a significant relationship with
diarrhea (p = 0.79).
Conclusion: Malnutrition, anemia, and rickets are strongly associated with diarrhea in children under five,
underscoring the need for integrated nutritional interventions. Addressing these comorbidities through early
detection, prevention, and targeted healthcare interventions can significantly improve child health outcomes.
Keywords: Diarrhea, Malnutrition, Anemia, Rickets, Integrated Management of Childhood Illness,
Pediatrics.
How to cite: Farooq MA, Mughal BB, Riaz Z, Shaukat A, Butt MR, Ayub A. Prevalence of Comorbidities Linked to
Integrated Management of Childhood Illness Among Children with Diarrhea. Esculapio - JSIMS 2025;21(01): 60-65
DOI: https://doi.org/10.51273/esc25.251321111
References
Adane M, Mengistie B, Kloos H, Medhin G, Mulat
W, Godana W, et al. Prevalence and determinants of
acute diarrhea among children under five years of age
in Eastern Ethiopia: A community-based cross
sectional study. BMC Public Health. 2023;23(1):1576.
DOI: 10.1186/s12889-023-16456
Rashid J. Shahid M. Bhatti MT. Burden of IMCI
Related Co-existing Illnesses than Diarrhea, in 2
Months to 5 year age children admitted in a tertiary
care unit: realizing the magnitude of problem?
PJMHS Online 2010:4(4):495-500.
Tetteh J, Kusi-Mensah Y, Agyemang S, Doku PN,
Yeboah-Antwi K. The burden of co-morbidities
among children under five presenting with diarrhea
in urban Ghana. BMC Pediatr. 2024;24(1):75. DOI:
1186/s12887-024-04456-3.
Sarker S, Hossain MA, Mousumi AA, Kakoli NJ,
Banik S, Razzaque MA, Mamunuzzaman M, Das PR.
Clinical Diagnosis of Severe Diseases According to
IMCI among Children in a Tertiary Care Hospital-A
Cross-Sectional Study. Sch J App Med Sci. 2023
J u n ; 6 : 1 0 7 0- 5 . DOI: 10.36347/
sjams.2023.v11i06.016.
George CM, Hasan MM, Monira S, Akter T, Barman
S, Mahfuz M, et al. Risk factors for diarrhea in
children under five in rural Bangladesh: A case
control study. BMJ Paediatr Open.
;7(1):e001545. DOI: 10.1136/bmjpo-2023
Levine GA, Walson JL, Atlas HE, Lamberti LM,
Pavlinac PB. Defining pediatric diarrhea in low
resource settings. Journal of the Pediatric Infectious
Diseases Society. 2017 Sep 1;6(3):289-93. DOI:
1093/jpids/piw061.
Gomez F, Galvan RR, Cravioto J, Frenk S.
Malnutrition in infancy and childhood, with special
reference to kwashiorkor. Advances in pediatrics.
Jan 1;7(1):131-69.
Ranjha AA, Qureshi EM, Ranjha HA, Abeer M,
Ranjha M. Frequency of Iron Deficiency Anemia and
Its Association with Persistent Diarrhea, Weight and
Parasitic Infestation in Children, 1-2 Years of Age in
Semi-Rural Area of District Sialkot, Pakistan: Iron
Deficiency Anemia and its Association. Pakistan
Journal of Health Sciences. 2023 Mar 31:88-93. DOI:
54393/pjhs.v4i03.460.
El-Desouky AI, Shaffi E, Mohammed M, Sharaf SM,
Mohammed HI. Association between Vitamin D
Deficiency and Recurrent Acute Diarrhea in
Children. The Egyptian Journal of Hospital
Medicine. 2020 Apr 1;79(1):538-43. DOI:
21608/ejhm.2020.85234.
Atari DO, Mkandawire P, Lukou YS. Determinants
of co-occurrences of diarrhea and fever among
children under five years of age in South Sudan.
African Geographical Review. 2023 Oct
0; 42(5):617-33. DOI: 10.1080/
2022.2150310.
Soboksa NE, Gari SR, Hailu AB, Mengistie Alemu B.
Childhood malnutrition and the association with
diarrhea, water supply, sanitation, and hygiene
practices in Kersa and Omo Nada Districts of Jimma
Zone, Ethiopia. Environmental Health Insights. 2021
Mar;15:1178630221999635. DOI:
1177/1178630221999635.
Islam MS, Chowdhury MR, Bornee FA, Chowdhury
HA, Billah B, Kader M, Rashid M. Prevalence and
determinants of diarrhea, fever, and coexistence of
diarrhea and fever in children under-five in
Bangladesh. Children. 2023 Nov 20;10(11):1829.
DOI: 10.3390/children10111829.
Chisenga CC, Bosomprah S, Mwaba J, Bwalya DL,
Simuyandi M. Risk factors for persistent diarrhea in
children under five years in Zambia. J Trop Pediatr.
;67(3):fmaa095. DOI: 10.1093/tropej/fmaa095.
Woyessa AH, Belachew T, Haileyesus F. Association
between childhood diarrhea and malnutrition in
Ethiopia: A systematic review and meta-analysis.
PLoS One. 2022;17(6):e0268956. DOI: 10.1371/
journal.pone.0268956.
Njuguna HN, Githuku JN, Oundo J, Boru WG.
Predictors of diarrhea among children aged 6–59
months in a resource-limited setting in Kenya. Int J
Pediatr. 2022;2022:8902435. DOI: 10.1155/2022/
Kooijman J, Huitema B, Gua. Diagnosis of Rickets in
Children: An Overview of Clinical and Radiological
Diagnosis. Pediatr Int. 2017;59(5):540-5. DOI:
1111/ped.13280.
Pavlinac PB, Denno DM, John-Stewart G, Onchiri
FM, Naulikha J, Odundo EA, et al. Failure of
standard case management of acute diarrhea in
children in low-resource settings: A systematic
review. Clin Infect Dis. 2021;72(12):2120-30. DOI:
1093/cid/ciaa1872.
Alabedi RF, Aljebouri AH, Al-Maaroof ZW. Acute
Otitis Media-Associated Diarrhea in Children Less
than 2 Years Old. Open Access Macedonian Journal
of Medical Sciences. 2022 May 15;10(B):1406-10.
DOI: 10.3889/oamjms.2022.9666.
Jordan N, Ranuh IG, Sari GM. Profile of diarrheal
patients aged less than five years old hospitalized in
Dr. Soetomo General Hospital Surabaya in 2016
Jurnal Ilmiah Mahasiswa Kedokteran
Universitas Airlangga. 2020;11(2):45-50. DOI:
20473/juxta.V11I22020.45-50
Bauhofer AF, Sambo J, Chilaúle JJ, Conjo C, Munlela
B, Chissaque A, Isaías T, Djedje M, de Deus N.
Examining comorbidities in children with diarrhea
across four provinces of Mozambique: A cross
sectional study (2015 to 2019). Plos one. 2023 Sep
;18(9):e0292093. DOI: 10.1371/
journal.pone.0292093.
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