Prevalence of Comorbidities Linked to Integrated Management of Childhood Illness Among Children with Diarrhea

Authors

  • Muhammad Azhar Farooq Associate Professor Pediatrics Unit - I SIMS/SHL
  • Binish Ali Assistant Professor Pediatrics Unit - I SIMS/SHL
  • Zunera Riaz Senior Registrar Pediatrics Services Insitute of Medical Sciences Lahore
  • Ayesha Shaukat SIMS/SHL
  • Maria Rizwan Butt Postgraduate Resident MD Pediatrics Services Insitute of Medical Sciences Lahore
  • Aqeela Ayub Associate Professor Pediatrics Services Insitute of Medical Sciences Lahore

DOI:

https://doi.org/10.51273/esc25.251321111

Keywords:

paediatric acute diarrhea, infection, malnutrition in children, nutritional rickets, Diarrhea,

Abstract

Abstract
Objective: This study aims to assess the prevalence of various comorbidities related to the Integrated
Management of Childhood Illness (IMCI) among children presenting with diarrhea.
Material and Methods: A descriptive cross-sectional study was conducted at the Department of Pediatrics,
Services Hospital Lahore (Ref No. IRB/2024/1410/SIMS dated 22.08.2024). A total of 383 children aged 1-5
years who presented with diarrhea were included using a non-probability consecutive sampling method.
Diarrhea was defined as the passage of three or more loose stools per day. The prevalence of IMCI-related
comorbidities including malnutrition, anemia, rickets, ear infections, and worm infestations was assessed
through clinical evaluation and laboratory tests. Data on demographic characteristics, breastfeeding and
weaning practices, vaccination status, and medical history were collected. Chi-square tests were used to
determine associations between comorbidities and diarrhea prevalence, with significance set at p ≤ 0.05.
Results: The study revealed a high prevalence of malnutrition (54.6%), anemia (55.9%), and rickets (30.8%)
among the children with diarrhea. Significant associations were observed between malnutrition, anemia, and
rickets (p < 0.001) with diarrhea prevalence. Ear infections were less common (4.17%) but still showed a
significant association (p = 0.049). Worm infestations, however, did not show a significant relationship with
diarrhea (p = 0.79).
Conclusion: Malnutrition, anemia, and rickets are strongly associated with diarrhea in children under five,
underscoring the need for integrated nutritional interventions. Addressing these comorbidities through early
detection, prevention, and targeted healthcare interventions can significantly improve child health outcomes.
Keywords: Diarrhea, Malnutrition, Anemia, Rickets, Integrated Management of Childhood Illness,
Pediatrics.
How to cite: Farooq MA, Mughal BB, Riaz Z, Shaukat A, Butt MR, Ayub A. Prevalence of Comorbidities Linked to
Integrated Management of Childhood Illness Among Children with Diarrhea. Esculapio - JSIMS 2025;21(01): 60-65
DOI: https://doi.org/10.51273/esc25.251321111

References

Adane M, Mengistie B, Kloos H, Medhin G, Mulat

W, Godana W, et al. Prevalence and determinants of

acute diarrhea among children under five years of age

in Eastern Ethiopia: A community-based cross

sectional study. BMC Public Health. 2023;23(1):1576.

DOI: 10.1186/s12889-023-16456

Rashid J. Shahid M. Bhatti MT. Burden of IMCI

Related Co-existing Illnesses than Diarrhea, in 2

Months to 5 year age children admitted in a tertiary

care unit: realizing the magnitude of problem?

PJMHS Online 2010:4(4):495-500.

Tetteh J, Kusi-Mensah Y, Agyemang S, Doku PN,

Yeboah-Antwi K. The burden of co-morbidities

among children under five presenting with diarrhea

in urban Ghana. BMC Pediatr. 2024;24(1):75. DOI:

1186/s12887-024-04456-3.

Sarker S, Hossain MA, Mousumi AA, Kakoli NJ,

Banik S, Razzaque MA, Mamunuzzaman M, Das PR.

Clinical Diagnosis of Severe Diseases According to

IMCI among Children in a Tertiary Care Hospital-A

Cross-Sectional Study. Sch J App Med Sci. 2023

J u n ; 6 : 1 0 7 0- 5 . DOI: 10.36347/

sjams.2023.v11i06.016.

George CM, Hasan MM, Monira S, Akter T, Barman

S, Mahfuz M, et al. Risk factors for diarrhea in

children under five in rural Bangladesh: A case

control study. BMJ Paediatr Open.

;7(1):e001545. DOI: 10.1136/bmjpo-2023

Levine GA, Walson JL, Atlas HE, Lamberti LM,

Pavlinac PB. Defining pediatric diarrhea in low

resource settings. Journal of the Pediatric Infectious

Diseases Society. 2017 Sep 1;6(3):289-93. DOI:

1093/jpids/piw061.

Gomez F, Galvan RR, Cravioto J, Frenk S.

Malnutrition in infancy and childhood, with special

reference to kwashiorkor. Advances in pediatrics.

Jan 1;7(1):131-69.

Ranjha AA, Qureshi EM, Ranjha HA, Abeer M,

Ranjha M. Frequency of Iron Deficiency Anemia and

Its Association with Persistent Diarrhea, Weight and

Parasitic Infestation in Children, 1-2 Years of Age in

Semi-Rural Area of District Sialkot, Pakistan: Iron

Deficiency Anemia and its Association. Pakistan

Journal of Health Sciences. 2023 Mar 31:88-93. DOI:

54393/pjhs.v4i03.460.

El-Desouky AI, Shaffi E, Mohammed M, Sharaf SM,

Mohammed HI. Association between Vitamin D

Deficiency and Recurrent Acute Diarrhea in

Children. The Egyptian Journal of Hospital

Medicine. 2020 Apr 1;79(1):538-43. DOI:

21608/ejhm.2020.85234.

Atari DO, Mkandawire P, Lukou YS. Determinants

of co-occurrences of diarrhea and fever among

children under five years of age in South Sudan.

African Geographical Review. 2023 Oct

0; 42(5):617-33. DOI: 10.1080/

2022.2150310.

Soboksa NE, Gari SR, Hailu AB, Mengistie Alemu B.

Childhood malnutrition and the association with

diarrhea, water supply, sanitation, and hygiene

practices in Kersa and Omo Nada Districts of Jimma

Zone, Ethiopia. Environmental Health Insights. 2021

Mar;15:1178630221999635. DOI:

1177/1178630221999635.

Islam MS, Chowdhury MR, Bornee FA, Chowdhury

HA, Billah B, Kader M, Rashid M. Prevalence and

determinants of diarrhea, fever, and coexistence of

diarrhea and fever in children under-five in

Bangladesh. Children. 2023 Nov 20;10(11):1829.

DOI: 10.3390/children10111829.

Chisenga CC, Bosomprah S, Mwaba J, Bwalya DL,

Simuyandi M. Risk factors for persistent diarrhea in

children under five years in Zambia. J Trop Pediatr.

;67(3):fmaa095. DOI: 10.1093/tropej/fmaa095.

Woyessa AH, Belachew T, Haileyesus F. Association

between childhood diarrhea and malnutrition in

Ethiopia: A systematic review and meta-analysis.

PLoS One. 2022;17(6):e0268956. DOI: 10.1371/

journal.pone.0268956.

Njuguna HN, Githuku JN, Oundo J, Boru WG.

Predictors of diarrhea among children aged 6–59

months in a resource-limited setting in Kenya. Int J

Pediatr. 2022;2022:8902435. DOI: 10.1155/2022/

Kooijman J, Huitema B, Gua. Diagnosis of Rickets in

Children: An Overview of Clinical and Radiological

Diagnosis. Pediatr Int. 2017;59(5):540-5. DOI:

1111/ped.13280.

Pavlinac PB, Denno DM, John-Stewart G, Onchiri

FM, Naulikha J, Odundo EA, et al. Failure of

standard case management of acute diarrhea in

children in low-resource settings: A systematic

review. Clin Infect Dis. 2021;72(12):2120-30. DOI:

1093/cid/ciaa1872.

Alabedi RF, Aljebouri AH, Al-Maaroof ZW. Acute

Otitis Media-Associated Diarrhea in Children Less

than 2 Years Old. Open Access Macedonian Journal

of Medical Sciences. 2022 May 15;10(B):1406-10.

DOI: 10.3889/oamjms.2022.9666.

Jordan N, Ranuh IG, Sari GM. Profile of diarrheal

patients aged less than five years old hospitalized in

Dr. Soetomo General Hospital Surabaya in 2016

Jurnal Ilmiah Mahasiswa Kedokteran

Universitas Airlangga. 2020;11(2):45-50. DOI:

20473/juxta.V11I22020.45-50

Bauhofer AF, Sambo J, Chilaúle JJ, Conjo C, Munlela

B, Chissaque A, Isaías T, Djedje M, de Deus N.

Examining comorbidities in children with diarrhea

across four provinces of Mozambique: A cross

sectional study (2015 to 2019). Plos one. 2023 Sep

;18(9):e0292093. DOI: 10.1371/

journal.pone.0292093.

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Published

2025-03-31

How to Cite

1.
Muhammad Azhar Farooq, Binish Ali, Zunera Riaz, Ayesha Shaukat, Maria Rizwan Butt, Aqeela Ayub. Prevalence of Comorbidities Linked to Integrated Management of Childhood Illness Among Children with Diarrhea. Esculapio - JSIMS [Internet]. 2025 Mar. 31 [cited 2025 May 13];21(1):60-5. Available from: https://esculapio.pk/journal/index.php/journal-files/article/view/60-65

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