Heart Rate Variability- A Predictive Tool for Analysis of Autonomic Dysfunction in Covid-19 Vaccinated Individuals

Abstract

Objective: To determine the association between gender and HRV values in COVID-19 vaccinated participants
and the difference in HRV in male and female COVID-19 vaccinated individual as compared to standard
value of HRV in healthy individuals
Method: An experimental, randomized control study was carried out in the department of physiology of Wah
Medical College, Wah Cantt, Pakistan for 3 months (April 2021 to June 2021). A total 100 vaccinated students of
1st year and 2nd year MBBS were divided into 2 groups, Female (Nf= 50) and Male Group (Nm= 50). Then
were further divided into three groups: (Group 1-HRV in above normal range), (Group 2- HRV in below
normal range), and (Group 3- HRV in normal standard range).
Results: 64.0% females had HRV value within standard reference range whereas 36.0% were below the
range. 44.0% males had HRV value within standard reference range, 28.0% were below the range and 28.0%
were above range. There was significant association (p < 0.001) between gender and HRV values in COVID-
19 vaccinated participants. The average HRV of male and female COVID-19 vaccinated individuals were
significantly different (p<0.001). The HRV of female vaccinated individuals was significantly different
where no difference was found in male vaccinated individuals, when compared with standard values.
Conclusion: COVID-19 vaccinated females are more prone to disturbance in autonomic modulation as
compared to males vaccinated individuals, thus at momentarily risk of cardiovascular events.

How to cite: Iqbal S, Iqbal S, Gul S, Shaukat A, Saher K. Heart Rate Variability- A Predictive Tool For Analysis Autonomic
Dysfunction in Covid-19 Vaccinated Individuals. Esculapio - JSIMS 2022;18(03):310-314
DOI: https://doi.org/10.51273/esc22.2518314