Osteoporosis in Peptic Ulcer Disease

Abstract

Objective: To determine the frequency of osteoporosis in cases with peptic ulcer disease.
Methods: It was a descriptive, cross sectional study that was conducted at Department of Medicine, Services Hospital, Lahore from January 2016 to September 2016. The cases presenting with history of epigastric pain with age range of 20 to 60 years of both gender were considered. These cases then underwent upper GI endoscopy and finally the 50 cases of peptic ulcer were considered. The detailed data was collected. The cases with previous history of bone trauma, metabolic disorders, end stage renal or liver disease and those with diabetes mellitus were excluded. The cases with diagnosed PUD then underwent DEXA scan and score less than 2.5 was labeled with osteoporosis.
Results: In this study there were total 50 cases out of which 28 were males and 22 females. The mean age was 37.14±4.27 years. The mean duration of PUD was 2.3±0.5 years and mean T score was 1.3±0.6. Osteoporosis was seen in 5 (10%) of cases. Osteoporosis was more seen in females affecting 03 (13.64%) cases of their respective groups (p= 0.07). There was no significant difference in terms of duration of PUD with osteoporosis (p= 0.78).
Conclusions: Osteoporosis is not uncommon in cases of peptic ulcer disease. Female gender is nearly significantly associated with this