Morphological spectrum of Lesions seen in Thyroidectomy Specimens at a Tertiary care Institute

Abstract

Objective: To determine the morphological spectrum of thyroid lesions encountered in thyroidectomy specimens at a tertiary care institute.
Methods: It was a retrospective study conducted in Pathology Department, Allama Iqbal Medical College, Lahore. A retrospective manual collection of data was done from record registers, for the years 2012 & 2013.
Results: A total of 307 cases were retrieved with age range of 16-70 years. Amongst them, 47 were males and 260 were females. Non neoplastic conditions outnumbered the neoplastic lesions as 229(75%) cases were of colloid goiter. Hashimoto thyroiditis was present in 12(3.9%) specimens and associated hyperplastic changes were seen in 15(4.9%) cases. There were 19(6.2%) cases of papillary carcinoma, 3(0.9%) cases of follicular carcinoma, 3(0.9%) cases of medullary carcinoma, 1(0.3 %) case of insular carcinoma and 2(0.6%) anaplastic carcinoma. Papillary microcarcinoma was seen in 4(1.3 %) cases and medullary microcarcinoma in 1(0.3%) case. Follicular adenoma comprised 29(9.4%) cases and Hurthle cell adenoma 3(0.9%) cases. Study data also showed 1(0.3%) rare case of hyalinizing trabecular tumor.
Conclusion: Non neoplastic thyroid diseases are more common as compared to neoplastic lesions. Papillary carcinoma is most common thyroid malignancy encountered in our setting.