Comparison of Short Term and Long Term Antibiotic Prophylaxis in Elective Lower Segment Cesarean Section

Abstract

Objectives: To compare efficacy of short term and long term antibiotic prophylaxis in terms of wound infection in patients undergoing elective LSCS.
Methods: A comparative study was conducted in Department of obstetrics and Gynecology, Hide here from Editors. Study duration was one year from January 1, 2012 to December 31 2012. A total 626 patients (313 in every group) were enrolled in the study. Group A received single dose of 3rd generation cephalosporin (cefriaxone) preoperatively as intravevous infusion 30 min before incision. Group B was given two doses ceftriaxone 12 hrly for 24hrs followed by 1st generation cephalosporin (cephradine) 500 mg oral antibiotic therapy for 5 days. Efficacy was compared between two group using chi-square test of independence. Data analysis was done on
SPSS version 10.
Results: A total of 65 out of 313 (20.9%) patients showed fever/wound infection in group A and 64/343 (20.4%) patients had fever /wound infection in group B. In Group A ,37 patients began showing fever/wound infection during hospital stay and 28 patients had fever/wound infection after discharge from hospital . In Group B, 35 patients had wound infection during four days of hospital stay and 29 had wound infection after discharge.
Conclusion: The short term and long term prophylaxis were equally effective in reducing morbidity, assessed by postoperative temperature and wound infection.