Association of Lifestyle Factors with Fetuin-A in Adolescents Having Familial Diabetic Background

Abstract

Objectives: A study was carried out to find the association of lifestyle factors with Fetuin-A in adolescents  having familial diabetic background.
Methods: Study was conducted in the department of Biochemistry and department of Pathology from  January 2019 to December 2019 at SIMS, SHL. Study included 35 self reported healthy male adolescents of ages 18-19 years having positive familial diabetic background (group A) whereas the subjects of same age and gender without familial diabetic background (relatives of type 2 diabetics) were placed in control group (group B). Type 2 diabetics and subjects having metabolic syndromes other than type 2 diabetes were excluded. Convenient sampling technique was used. A questionnaire based on demographic variables including lifestyle and eating habits was filled by study subjects after their informed consent. Serum levels of fasting blood glucose were estimated by autoanalyzer (HUMAN) and insulin and Fetuin-A by ELISA. Data
was analyzed by SPSS 20.
Results: It was observed that 67% of total study subjects were having sedentary lifestyle and using energy dense diet and beverages in routine and found to have relatively higher levels of fasting blood sugar, serum insulin and serum Fetuin-A. However, when two groups were compared, statistically significant increase in levels of serum Fetuin-Awas observed in group.
Conclusion: An association was observed between sedentary lifestyle, dietary pattern, and Fetuin-A in adolescents having familial diabetic background (group A).