Comparison of Pulmonary Function Test in Controlled and Uncontrolled Type 2 Diabetes Mellitus Patients in Pakistan

Authors

Zunaira Azher Department of Physiology, Services institute of medical science, Lahore.
Muhammad Imran Consultant Physician Medicine DHQ Hospital ,Kasur.

DOI:

Keywords:

Type 2 diabetes, Pulmonary function test, Controlled diabetes, Uncontrolled diabetes, HbA1c

Abstract

Abstract
Objective: Compare Pulmonary function test in controlled and uncontrolled type 2 diabetes mellitus
patients.
Material and Methods: This case control study was conducted in outpatient department of chest department
of the university of Lahore teaching hospital Lahore from 14 march 2016 to 14 september 2016 with IRB
number ref-IMBB/BBBC/16/264. After approval of IRB. All patients and controls who fulfil selection
criteria were considered in this research. Informed consent was taken from every patient. Demographic
profile (name, age, sex, contact no.) was obtained. Only those patients whose fasting blood sugar were >126
mg/dl or random blood sugar >200 mg/dl were selected. The HbA1c was also estimated in order to
differentiate between controlled (<7) and uncontrolled diabetes (>7).
Results: In this study, no statistically significant difference was seen between mean ranks for FVC [Group-
A:86.91, Group-B: 74.00 & Group-C: 83.59], FEV1 [Group-A:88.44, Group-B: 80.56 & Group-C: 75.50]
and FEF (25-75) [Group-A:87.53, Group-B: 80.73 & Group-C:76.23] among the study group. However,
FEV/FVC significantly differ across the groups. i.e. [Group-A:98.18, Group-B: 109.41 & Group-C: 36.91].
Multiple comparison test showed that no statistical difference was seen for FEV/FVC between Group-A and
in Group-B patients. However, between Group-A and Group-C and Group-B and Group-C statistically
significant difference was seen.
Conclusion: Results of this study showed that uncontrolled diabetes adversely effects pulmonary function
and causes significant lung function impairment.
Keywords: Type 2 diabetes, Pulmonary function test, Controlled diabetes, Uncontrolled diabetes, HbA1c
How to cite: Azher Z, Imran M. Comparison of Pulmonary Function Test in Controlled and Uncontrolled Type 2
Diabetes Mellitus Patients in Pakistan. Esculapio - JSIMS 2025;21(01): 15-19
DOI: https://doi.org/10.51273/esc25.2513213

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Published

2025-05-12

How to Cite

Zunaira Azher, Muhammad Imran. Comparison of Pulmonary Function Test in Controlled and Uncontrolled Type 2 Diabetes Mellitus Patients in Pakistan. Esculapio - JSIMS [Internet]. 2025 May 12 [cited 2025 May 13];21(1):15-9. Available from: https://esculapio.pk/journal/index.php/journal-files/article/view/1325