Dietary Habits, Physical Activity and Enviornmental Toxicology Role in Type-II Diabetes Mellitus

Authors

  • dr. ahmad raza khan khan Office of Surgeon Medicolegal Punjab, Lahore
  • Alaita Fatima Bakhtiari, Pakistan Kidney and Liver Institute and Research Centre - PKLI.
  • Fariha Tariq King Edward Medical College Lahore
  • Khalid Mahmood Forensic Medicine and Toxicology.
  • Fozia Bibi CMH Kharian Medical College, Kharian Cantt.
  • Khizar Hayat Pak Red Crescent Medical and Dental College.

DOI:

https://doi.org/10.51273/esc25.251321124

Keywords:

Diabetes, physical activity, type 2 diabetes mellitus

Abstract

Abstract
Objective: To correlation between life style, diet and environmental pollution in type 2 diabetes mellitus.
Material and Methods: It was a cross sectional study of comparative data analysis of glycemic levels among
population regarding environment, diet and physical activity. Sample size calculated was 228.
Results: The study included 228 participants who were randomly sampled from Services Hospital Lahore
including patients as well as the accompanying attendants coming in from urban and surrounding rural area
of Lahore. The variables specified for research were diet and lifestyle of a subjects from both urban and rural
setups. The final result showed that 64% (147 out of 228) participants were normoglycemic, 6% were Pre
diabetic and 36% (81 out of 228) were of type 2 diabetes mellitus.
Conclusion: Diet and physical activity were the main cofactors along with pollution scenario, having an
etiological role in type II Diabetes Mellitus.
Keywords: Diabetes mellitus, pollution, organic diet, physical activity.
How to cite: Khan AR, Bakhtiari AF, Tariq F, Mahmood K, Bibi F, Hayat K. Dietary Habits, Physical Activity and
Enviornmental Toxicology Role in Type II Diabetes Mellitus - JSIMS 2025;21(01): 134-139
DOI: https://doi.org/10.51273/esc25.251321124

References

References

Genchi, G.; Carocci, A.; Lauria, G.; Sinicropi, M. S.;

Catalano, A., Nickel: Human health and

environmental toxicology. International journal of

environmental research and public health 2020, 17

(3), 679. https://doi.org/10.3390/ijerph17030679.

Asha, P.; Natrayan, L.; Geetha, B.; Beulah, J. R.;

Sumathy, R.; Varalakshmi, G.; Neelakandan, S., IoT

enabled environmental toxicology for air pollution

monitoring using AI techniques. Environmental

research 2022, 205, 112574. https://doi.org/

1016/j.envres.2021.112574.

Meo, S. A., Environmental Pollution and Type 2

Diabetes Mellitus. Elsevier: 2024.

https://doi.org/10.1016/C2022-0-03238-4.

Lawrence, J. M.; Divers, J.; Isom, S.; Saydah, S.;

Imperatore, G.; Pihoker, C.; Marcovina, S. M.;

Mayer-Davis, E. J.; Hamman, R. F.; Dolan, L., Trends

in prevalence of type 1 and type 2 diabetes in children

and adolescents in the US, 2001-2017. Jama 2021,

(8), 717-727. doi:10.1001/jama.2021.11165.

Farmaki, P.; Damaskos, C.; Garmpis, N.; Garmpi, A.;

Savvanis, S.; Diamantis, E., Complications of the

type 2 diabetes mellitus. Current cardiology reviews

, 16 (4), 249-251. https://doi.org/10.2174/

X1604201229115531.

Luc, K.; Schramm-Luc, A.; Guzik, T.; Mikolajczyk,

T., Oxidative stress and inflammatory markers in

prediabetes and diabetes. Journal of Physiology &

Pharmacology 2019, 70 (6). . DOI: 10.26402/

jpp.2019.6.01.

Arcambal, A.; Taïlé, J.; Rondeau, P.; Viranaïcken, W.;

Meilhac, O.; Gonthier, M.-P., Hyperglycemia

modulates redox, inflammatory and vasoactive

markers through specific signaling pathways in

cerebral endothelial cells: Insights on insulin

protective action. Free Radical Biology and

Medicine 2019, 130, 59-70. https://doi.org/10.1016/

j.freeradbiomed.2018.10.430.

Olsson, K.; Ramne, S.; González-Padilla, E.;

Ericson, U.; Sonestedt, E., Associations of

carbohydrates and carbohydrate-rich foods with

incidence of type 2 diabetes. British Journal of

Nutrition 2021, 126 (7), 1065-1075. https://doi.org

1017/s0007114520005140.

Rakhis Sr, S. A. B.; AlDuwayhis, N. M.; Aleid, N.;

AlBarrak, A. N.; Aloraini, A. A., Glycemic control for

type 2 diabetes mellitus patients: a systematic review.

Cureus 2022, 14 (6).

doi:

7759/cureus.26180.

Dong, G.; Qu, L.; Gong, X.; Pang, B.; Yan, W.; Wei,

J., Effect of social factors and the natural

environment on the etiology and pathogenesis of

diabetes mellitus. International Journal of

Endocrinology 2019, 2019 (1), 8749291.

https://doi.org/10.1155/2019/8749291.

Atkinson, F. S.; Brand-Miller, J. C.; Foster-Powell,

K.; Buyken, A. E.; Goletzke, J., International tables

of glycemic index and glycemic load values 2021: a

systematic review. The American journal of clinical

nutrition 2021, 114 (5), 1625-1632. https://doi.org/

2337/dc08-1239.

Suárez, R.; Chapela, S. P.; Álvarez-Córdova, L.;

Bautista-Valarezo, E.; Sarmiento-Andrade, Y.;

Verde, L.; Frias-Toral, E.; Sarno, G., Epigenetics in

obesity and diabetes mellitus: new insights. Nutrients

, 15 (4), 811. https://doi.org/10.3390/

nu15040811.

Misra, B. B.; Misra, A., The chemical exposome of

type 2 diabetes mellitus: Opportunities and

challenges in the omics era. Diabetes & Metabolic

Syndrome: Clinical Research & Reviews 2020, 14

( 1), 23-38. https://doi.org/10.1016/

j.dsx.2019.12.001.

Khalil, W. J.; Akeblersane, M.; Khan, A. S.; Moin, A.

S. M.; Butler, A. E., Environmental pollution and the

risk of developing metabolic disorders: obesity and

diabetes. International Journal of Molecular Sciences

, 24 (10), 8870.

https://doi.org/10.3390/

ijms24108870.

Li, Y.; Xu, L.; Shan, Z.; Teng, W.; Han, C.,

Association between air pollution and type 2

diabetes: an updated review of the literature.

Therapeutic advances in endocrinology and

metabolism 2019, 10, 2042018819897046.

https://doi.org/10.1177/2042018819897046.

Subhani, M. A.; Anwar, M. N.; Nizami, A.-S.; Ashraf,

U.; Khokhar, M. F., An Emerged Challenge of Air

Pollution and Ever-Increasing Particulate Matter in

Pakistan; A Critical Review. Journal of Hazardous

Mat e r i a l s 2 0 21, 402, 123943.

https://doi.org/10.1016/j.jhazmat.2020.123943.

Mercado, C. I.; McKeever Bullard, K.; Gregg, E. W.;

Ali, M. K.; Saydah, S. H.; Imperatore, G.,

Differences in US rural-urban trends in diabetes

ABCS, 1999–2018. Diabetes Care 2021, 44 (8),

-1773. https://doi.org/10.2337/dc20-0097.

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Published

2025-03-31

How to Cite

1.
khan dr. ahmad raza khan, Alaita Fatima Bakhtiari, Fariha Tariq, Khalid Mahmood, Fozia Bibi, Khizar Hayat. Dietary Habits, Physical Activity and Enviornmental Toxicology Role in Type-II Diabetes Mellitus. Esculapio - JSIMS [Internet]. 2025 Mar. 31 [cited 2025 May 13];21(1):134-9. Available from: https://esculapio.pk/journal/index.php/journal-files/article/view/1304

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