Role of Autologous Bone Marrow Injection in Treatment of Long Bones Delayed Union

Authors

Arif Mahmood Services Insititute of Medical Sciences
Sohail Razzaq Services Insitute of Medical Sciences Lahore
Mehran Khan Services Insitute of Medical Sciences Lahore
Maqsood Akhtar Services Insitute of Medical Sciences Lahore
Muhammad Noman Services Insitute of Medical Sciences Lahore

DOI:

Keywords:

Success, , Percutaneous, Autologous, Bone marrow, , Injections, , Management

Abstract

Abstract
Objective: To assess the frequency of success of percutaneous autologous bone marrow injections for
management of delayed union of long bone.
Material and Methods: Study design- Descriptive case series Setting: Department of Orthopedic Surgery,
Services Hospital, Lahore. Duration: One year 01-09-2023 to 30–08-2024 Data collection procedure: After
approval from IRB, informed consent was taken. 65 patients fulfilling the inclusion criteria were admitted
through OPD and received percutaneous bone marrow injection (40-80ml) at fracture site by a single surgical
team under anesthesia with fluoroscope guidance. After discharge patients were followed in OPD for 6
months with radiographs. Success was labeled If complete callus was seen on radiographs within 6 months.
Results: Mean age was 40.03±13.24 years with 33(50.8%) male and 32(49.2%) female. Mean duration of
previous treatment was 5.20±0.85 months. Success was seen in 54(83.1%) patients. Success rate was higher
in the younger age group p-value=0.002. There was no effect of gender and duration of prior treatment in
achieving union. Success rate of percutaneous autologous bone marrow injections was seen in 83.1%.
Conclusion: The autologous bone marrow injections at the fracture site is simple and effective method in
delayed union of long bones to achieve union.
Keywords: Success, Percutaneous, Autologous, Bone marrow, Injections, Management, Delayed, Union,
Long bone
How to cite: Mahmood A, Razzaq S, Khan M, Akhtar M, Noman M. Role of Autologous Bone Marrow Injection in
Treatment of Long Bones Delayed-Union. Esculapio - JSIMS 2025;21(01): 36-40
DOI: https://doi.org/10.51273/esc25.2513217

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Published

2025-05-12

How to Cite

Arif Mahmood, Sohail Razzaq, Mehran Khan, Maqsood Akhtar, Muhammad Noman. Role of Autologous Bone Marrow Injection in Treatment of Long Bones Delayed Union. Esculapio - JSIMS [Internet]. 2025 May 12 [cited 2025 Jun. 6];21(1):36-40. Available from: https://esculapio.pk/journal/index.php/journal-files/article/view/1299