Screening of Undiagnosed Hyperglycemia and Elevated Blood Pressure in Periodontitis Patients

Authors

  • Muhammad Haseeb University College of Dentistry, The University of Lahore
  • Sittara Javed University College of Dentistry, The University of Lahore
  • Naima Khalid Fatima Memorial College of Medicine and Dentistry
  • Zubair Ahmed Khan Fatima Memorial College of Medicine and Dentistry
  • Farheen Qureshi Fatima Memorial College of Medicine and Dentistry
  • Maqbool Ahmad University College of Dentistry, The University of Lahore

DOI:

https://doi.org/10.51273/esc25.251321132

Keywords:

Hyperglycemia, Hypertension, Periodontal Health, Periodontal disease Opportunistic screening.

Abstract

Abstract
Objective: To evaluate the prevalence of previously undiagnosed hyperglycemia and hypertension in dental
settings and their association with periodontal health.
Material and Methods: Conducted at The University College of Dentistry, University of Lahore, this cross
sectional study included 322 individuals aged 20 and above, selected through purposive sampling from the
Periodontology outpatient department. After institutional review board approval, blood pressure readings
were taken using a digital sphygmomanometer 15 minutes after patient arrival. Blood glucose levels were
measured using a glucometer. Periodontal health was assessed using periodontal charting and the Basic
Periodontal Examination (BPE) scoring technique. Statistical analysis, including chi-square tests and
descriptive analysis, was performed to evaluate associations.
Results: Among 322 participants (mean age: 46 years), 27% were previously undiagnosed hypertensive, and
13.1% were hyperglycemic. Blood pressure ranged from 99/60 mmHg to 218/120 mmHg, while blood
glucose varied from 67 mg/dL to 439 mg/dL. Periodontal health assessment revealed that 38.8% had BPE
Code 3 and 10.2% had Code 4, both significantly associated with unknown hyperglycemia and hypertension.
Gingivitis was more prevalent in those under 50 years, whereas periodontitis was common in older
individuals. Patients with mean arterial pressure >100 mmHg showed a higher inclination toward
periodontitis.
Conclusion: The findings highlight the importance of opportunistic screening in dental settings for early
detection of hyperglycemia and hypertension. A significant correlation between these conditions and
periodontal health underscores the need for integrated healthcare approaches.
Keywords: Hyperglycemia, Hypertension, Periodontal Health, Periodontal Disease, Opportunistic
Screening.
How to cite: Haseeb M, Javed S, Khalid N, Khan ZA, Qureshi F, Ahmad M. Screening of Undiagnosed Hyperglycemia
and Elevated Blood Pressure in Periodontitis Patients. Esculapio - JSIMS 2025;21(01): 181-187
DOI: https://doi.org/10.51273/esc25.251321132

Author Biographies

Muhammad Haseeb, University College of Dentistry, The University of Lahore

Periodontology, Associate Professor

Sittara Javed, University College of Dentistry, The University of Lahore

Periodontology Department, Senior Registrar, Univerisity College of Dentistry, The University of Lahore

Naima Khalid, Fatima Memorial College of Medicine and Dentistry

Periodontology Department, Post-graduate resident, Fatima Memorial collage of Medicine and Dentistry

Zubair Ahmed Khan, Fatima Memorial College of Medicine and Dentistry

Periodontology Department, Associate Professor, Fatima Memorial College of Medicine and Dentistry

Farheen Qureshi, Fatima Memorial College of Medicine and Dentistry

Periodontology Department, Assisstant Professor, Fatima Memorial College of Medicine and Dentistry

Maqbool Ahmad, University College of Dentistry, The University of Lahore

Periodontology Department, Post-graduate resident, University College of Dentistry, The University of Lahore

References

References

Metzger BE, Coustan DR, Trimble ER.

Hyperglycemia and adverse pregnancy outcomes.

Clinical chemistry. 2019 Jul 1;65(7):937-8. DOI:

1373/clinchem.2019.303990.

Khurshid R, Ashraf H, Ahmed F. Insulin Resistance

and Beta-cell Function in Adolescent Hypertensive

Patients. 2018;14(03):17–20. DOI: https://doi.org/

51273/esc18.714310.

Jamshaid T. Diabetes Mellitus–The Epidemic of 21

Century. Esculapio J SIMS. 023;19(01):1–2. DOI:

https://esculapio.pk/journal/index.php/journal

files/article/view/272

Aslam R, Suhail S, Sajid R, Younis B bin. Type 2

Diabetes Mellitus(T2DM) in Pakistan: Prevalence,

Trends and Management Strategies. Ann King

Edward Med Univ. 2022;28(2):247–54. DOI:

https://doi.org/10.21649/akemu.v28i2.5117.

Meo SA, Zia I, Bukhari IA, Arain SA. Type 2 diabetes

mellitus in Pakistan: Current prevalence and future

forecast. JPMA. The Journal of the Pakistan Medical

Association. 2016 Dec 1;66(12):1637-42. PMID:

López MD, Álvarez MD. La diabetes mellitus y su

vinculación en la etiología y patogenia de la

enfermedad periodontal. Gaceta medica espirituana.

Mar 23;9(2):14. DOI: https://

revgmespirituana.sld.cu/index.php/gme/article/view

/794.

Del Pinto R, Landi L, Grassi G, Sforza NM, Cairo F,

Citterio F, Paolantoni G, D'aiuto F, Ferri C, Monaco

A, Pietropaoli D.Hypertension and periodontitis: A

joint report by the Italian society of hypertension

(SIIA) and the Italian society of periodontology and

implantology (SIdP). High Blood Pressure &

Cardiovascular Prevention. 2021 Sep;28:427-38.

DOI: 10.1007/s40292-021-00466-6.

Pirih FQ, Monajemzadeh S, Singh N, Sinacola RS,

Shin JM, Chen T, Fenno JC, Kamarajan P, Rickard

AH, Travan S, Paster BJ. Association between

metabolic syndrome and periodontitis: The role of

lipids, inflammatory cytokines, altered host

response, and the microbiome. Periodontology 2000.

Oct;87(1):50-75. DOI: 10.1111/prd.12379.

Rafique A, Ahsen MI, Khattak MU, Ali MY, Javed S,

Khalid Q. Prevalence of Gingival Inflammation

among Patients Taking Antipsychotic Drugs.

Pakistan J Med Heal Sci. 2022;16(12):480–2 . DOI:

https://doi.org/10.53350/pjmhs20221612480.

Llambés F. Relationship between diabetes and

periodontal infection. World J Diabetes.

;6(7):927. DOI: 10.4239/wjd.v6.i7.927.

Barbadoro P, Ponzio E, Coccia E, Prospero E,

Santarelli A, Rappelli GG, D'Errico MM. Association

between hypertension, oral microbiome and salivary

nitric oxide: A case-control study. Nitric Oxide. 2021

Jan 1;106:66-71. DOI: 10.1016/j.niox.2020.11.002.

Bossart M, Calley K, Gurenlian JR, Mason B,

Ferguson R, Peterson T. A pilot study of an HbA1c

chairside screening protocol for diabetes in patients

with chronic periodontitis: The dental hygienist's

role. Int J Dent Hyg. 2016;14(2):98–107. DOI:

1111/idh.12140.

Herman WH, Taylor GW, Jacobson JJ, Burke R,

Brown MB. Screening for prediabetes and type 2

diabetes in dental offices. J Public Health Dent.

;75(3):175–82. DOI: 10.1111/jphd.12082.

Center H. Companion Action Guide >> Evidence

Based Care CARE DELIVERY PEOPLE

INFRASTRUCTURE This Evidence-Based

Companion Guide on Hypertension (HTN) screening

and control offers evidence-based steps to identify

and manage HTN. It serves as a road map for health

centers to identify and manage HTN within the

context of whole person care when used with the

Evidence-Based Care Action Guide. 2021;(January

. DOI: 10.1161/CIRCRESAHA.121.318083.

Machado V, Aguilera EM, Botelho J, Hussain SB,

Leira Y, Proença L, et al. Association between

periodontitis and high blood pressure: Results from

the study of periodontal health in almada-seixal

(sophias). J Clin Med. 2020;9(5):1–13. DOI:

3390/jcm9051585.

Alwithanani N. Periodontal Diseases and Diabetes

Mellitus: A Systematic Review. Journal of Pharmacy

and Bioallied Sciences. 2023 Jul 1;15(Suppl 1):S54

DOI: 10.4103/jpbs.jpbs_515_22.

Palareti G, Legnani C, Cosmi B, Antonucci E, Erba

N, Poli D, et al. Comparison between different D

Dimer cutoff values to assess the individual risk of

recurrent venous thromboembolism: Analysis of

results obtained in the DULCIS study. Int J Lab

Hematol. 2016;38(1):42–9. DOI: https://doi.org/

1111/ijlh.12426.

Simpson TC, Weldon JC, Worthington HV,

Needleman I, Wild SH, Moles DR, Stevenson B,

Furness S, Iheozor‐Ejiofor Z. Treatment of

periodontal disease for glycaemic control in people

with diabetes mellitus. Cochrane Database of

Systematic Reviews. 2015(11). DOI:

1002/14651858.CD004714.pub3.

Kowall B, Holtfreter B, Völzke H, Schipf S, Mundt T,

Rathmann W, Kocher T. Pre‐diabetes and

well‐controlled diabetes are not associated with

periodontal disease: the SHIP Trend Study. Journal of

clinical periodontology. 2015 May;42(5):422-30.

DOI: 10.1111/jcpe.12391.

Elahi A, Ali AA, Khan AH, Samad Z, Shahab H, Aziz

N, Almas A. Challenges of managing hypertension in

Pakistan-a review. Clinical Hypertension. 2023

Dec;29(1):1-4. DOI: https://doi.org/10.1186/

s40885-023-00245-6.

Elias MF, Goodell AL. The need for accurate data on blood pressure

measurement in the dental office. Am J Hypertens.

;33(4):297–300. PMID: 32124913.Gao Q, Lin

Y, Xu R, Zhang Y, Luo F, Chen R, et al. Association

between mean arterial pressure and clinical outcomes

among patients with heart failure. ESC Hear Fail.

;10(4):2362–74. PMID: 37177860

Downloads

Published

2025-03-31

How to Cite

1.
Muhammad Haseeb, Sittara Javed, Naima Khalid, Zubair Ahmed Khan, Farheen Qureshi, Maqbool Ahmad. Screening of Undiagnosed Hyperglycemia and Elevated Blood Pressure in Periodontitis Patients. Esculapio - JSIMS [Internet]. 2025 Mar. 31 [cited 2025 May 13];21(1):185-91. Available from: https://esculapio.pk/journal/index.php/journal-files/article/view/1230

Issue

Section

Original Articles