Comparison of the Local Anesthetic Effect of Two Doses of Dexmedetomidine , 5µg and 10µg added to Intrathecal Hyperbaric Bupivacaine

Abstract

Objective:To Ascertain the optimum intrathecal dose of dexmedetomidine along with local anesthetic.
Method: Prospective randomized study, Place and Duration of Study was in the Department of Anaesthesia, FMHCollege ofMedicine&Dentistry,Lahore from1st.February to 31st.July (6months) 2021. Ninety patients posted for urological, lower abdominal and pelvic general surgical procedures selected for the study were distributed in three groups. All groups comprised 30 patients each. Our facility is providing treatment to infertile males and that was our main study population.We selectedASA1&2 patients between 20 and 60 years.The first group [Control (C)] received only local anesthetic (2 ml. of hyperbaric bupivacaine 0.75%) plus 0.5 ml normal saline. The second group [Dexmedetomidine (D1)] received in addition to local anesthetic 5 micrograms of dexmedetomidine.The third group [Dexmedetomidine (D2)]received in addition to local anesthetic 10 µg of dexmedetomidine. The duration of surgical anesthesia, motor blockade and severity of side effects (hypotension and bradycardia) were noted for all patients in all the three groups. All the groups received 2.5 ml intrathecal injection.
Results: The onset of the blockade was similar in all groups. The duration of block was maximally prolonged in (D2) group. The duration was in between in (D1) group. It was minimum in (C) group.
Conclusion: Intrathecal use of dexmedetomidine with local anesthetic prolonged the sensory and motor blockade and 5 µg was found to be the optimal dose.

How to cite: Abaidullah K, Siddiqi KJ, Khan MA, Ahmad M, Awais M. Khalid R. Comparison of the Local Anesthetic
Effect of Two Doses of Dexmedetomidine , 5µg and 10µg added to Intrathecal Hyperbaric Bupivacaine Esculapio -
JSIMS 2022;18(04):248-252