Polycythemia vera with metastatic adenocarcinoma in bone marrow in a 68-year-old male

Abstract

The co-occurrence of polycythemia vera (PV) and metastatic adenocarcinoma in bone marrow is rare. The present case study describes a case of PV in association with metastatic carcinoma in the bone marrow. Magnetic resonance imaging (MRI) pelvis (for hip joints) revealed suspicious bone marrow changes in the lumbosacral spine. The bone marrow biopsy indicated hyperplastic trilineage hematopoiesis along with non-hemopoietic cells. The findings of immunohistochemistry on the trephine biopsy sample indicated the gastrointestinal origin of metastatic non-hematopoietic cells. The present study may help in the future management of patients with polycythemia vera and metastatic adenocarcinoma.