Frequency of Solid Pediatric Tumors in Tertiary Care Hospital in Lahore

Abstract

Objective: To see the frequency of benign and malignant solid pediatric tumors.
Material and Methods: A prospective descriptive study were conducted in Pathology department, University
of Child Health Sciences, Children Hospital, Lahore, from January, 2023-December, 23. Histological diagnosis
was made on hematoxylin and eosin-stained slides. Immunostaining was also done. Data analysis were done
by Statistical Package for the Social Sciences (SPSS) Version 20 and expressed as frequency and percentage.
Results: There were 17 cases of benign tumors of which 10 were females and 7 were males. Mature cystic
teratoma was the most common benign tumor. Out of 100 cases of solid malignant tumors 71% were males and
29% were females There were 17 cases of NHL (17%), and all were seen in males with ages from 1-13 years.
Whereas, the cases of Hodgkin's disease were 11 (11%). This was also prevalent more in males, the ratio being
9:2. Neuroblastoma was the second most common solid pediatric malignancy (17%) seen in age group1-13
year. Male to female ratio was 12:5. Third most common malignant tumor found was Wilms tumor (13%).
Conclusion: Lymphoma is the most common solid malignant tumor in children followed by neuroblastoma
and Wilms tumor. The incidence of malignant tumors is more in males, whereas benign tumors are seen more
in females.
Keywords: Hodgkin's lymphoma, non-Hodgkin's lymphoma, Neuroblastoma, Wilms tumor.