Concurrent Infection of Severe Malaria and Dengue Hemorrhagic Fever

Authors

Omair Farooq Assistant Professor, Department of Medicine, Farooq Hospital
Muhammad Ahmad Akhtar Saeed Medical and Dental College
Maryam Rashid Professor Pharmacology, Akhtar Saeed Medical and Dental College Lahore
Amna Maqsood Akhtar Saeed Medical and Dental College, Lahore
Johar Raza Senior Registrar, Farooq Hospital, Lahore.

DOI:

https://doi.org/10.51273/esc25.251321134

Keywords:

Dengue, Malaria, Co-infection, Sepsis

Abstract

Abstract: Dengue and Malaria are common infections in tropical regions but infection at the same time with
both is a growing threat, particularly in tropical regions where both diseases are endemic. The case being
reported is a 29-year-old male, presented with fever, rigors, abdominal pain, and drowsiness. His condition
rapidly deteriorated, developing respiratory acidosis, acute kidney injury, and coagulopathy with
hematemesis. Blood tests confirmed co-infection with cerebral malaria and dengue hemorrhagic fever.
Despite aggressive treatment with ventilation, broad-spectrum antibiotics, multiple blood transfusions,
plasma transfusions and hemodialysis, he developed ventilator-associated pneumonia, and Clostridium
difficile secondary to broad-spectrum IV antibiotics. After 16 days of intensive care, his condition improved,
and he was discharged. This case highlights the challenges of diagnosing and managing co-infection with
severe malaria and dengue, where rapid deterioration can multi-organ failure can occur and can be potentially
fatal.
Keywords: Dengue, Cerebral Malaria, Co-Infection, Fulminant Falciparum Malaria
How to cite: Farooq O, Ahmad M, Rashid M, Maqsood A, Raza J. Concurrent Infection of Severe Malaria and Dengue
Hemorrhagic Fever. Esculapio - JSIMS 2025;21(01):192-194
DOI: https://doi.org/10.51273/esc25.251321134

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Published

2025-03-31

How to Cite

Omair Farooq, Muhammad Ahmad, Maryam Rashid, Amna Maqsood, Johar Raza. Concurrent Infection of Severe Malaria and Dengue Hemorrhagic Fever. Esculapio - JSIMS [Internet]. 2025 Mar. 31 [cited 2025 Jun. 6];21(1):196-8. Available from: https://esculapio.pk/journal/index.php/journal-files/article/view/1149