Estimation of Pulmonary Function Tests in Pre and Post-menopausal Women

Abstract

Objective: To ascertain if post-menopausal women are more susceptible to a decline in pulmonary functions
(PFTs) as compared to premenopausal women.
Method: This cross-sectional comparative study was conducted at Physiology Department, FPGMI, Shaikh
Zayed Hospital, Lahore from May 2019-May 2020. We recruited one hundred and twenty premenopausal
women in age range of 40-50 years (group 1) and one hundred and twenty postmenopausal women with upper
age limit of 55 years (group 2). After informed written consent, a detailed questionnaire regarding
demographic data was recorded. Pulmonary functions were estimated by spirometry and compared between
the two groups. Data were analyzed by SPSS version 20.
Results: Pulmonary functions were markedly declined in postmenopausal women as compared to
premenopausal women. Percent predicted value for age for FEV1, FVC and FEV1/FVC in group 1 were
83.01±2.69%, 83.49±2.55% and 0.897 ±0.004% respectively. In group 2 these were 78.49±1.19%, 78.13±1.38%
and 1.03 ±0.01% respectively. The differences between two groups were statistically significant (independent
sample t test for FEV1 and FVC (p = 0.001 &0.002 respectively and Mann- Whitney U test for FEV1/FVC
0.0002)
Conclusion: It was concluded that pulmonary functions are compromised in post-menopausal women.

How to cite: Zareen S, Saduf M. Zahid H, Rasheed S, Zulfiqar S, Bokhari FA. Estimation of Pulmonary Function Tests in Pre and
Post-menopausal Women. Esculapio - JSIMS 2022;18(01):20-24.