Association Between Hyperglycemia and Short-term Outcome in Patients with Ischemic Stroke

Abstract

Objective: To find association between Hyperglycemia and short-term outcome on patients with ischemic stroke.
Material and Methods: A prospective cohort study was conducted in Neurology Department, Sir Ganga Ram Hospital. Study was conducted for 6 months and it included 60 patients. Fasting blood glucose and 2 hours postprandial blood glucose level and history of Diabetes Mellitus (DM) was recorded on 1st day of admission. HbA1C was measured at baseline. All the patients were assessed at 1st admission day as per the modified Rankin Scale (mRS) and were managed as per policy of the department. Patients were followed up on 30th post-stroke day after discharge. On 30th day, they were assessed by mRS, and short-term poor outcome was recorded in both groups.
Results: Relative risk for poor outcome among exposed patients was 4.20 which means that patients in exposed group had 4.20 times more chances of poor outcome as compared to unexposed patients. Patients in the age group 24-35 and 46-55 years had 15.16 and 11 times higher risk for poor outcome in patients with uncontrolled diabetes. The mean age of patients in exposed and unexposed group was 51.30±14.18 and 43.96±13.12 years.
Conclusion: Uncontrolled diabetes was significantly associated with and poses a high risk for short-term poor outcome in ischemic stroke patients.
Keywords: Ischemic stroke, Uncontrolled, Diabetes mellitus, Short term, Outcome