Wilms Tumor Different Histology Patterns Observed in Tertiary Care Hospital

Authors

  • Bushra Nisar Children Hospital Lahore
  • Saadia Sharif The University of Lahore-Pakistan
  • Abeer Zaheer Children Hospital Lahore
  • Samina Zaman Children Hospital Lahore
  • Mehwish Hussain Children Hospital Lahore
  • Zunaira Jamshed Fatima memorial Hospital Lahore
  • Tayyaba Yasin The University of Campania Luigi Vanvitelli, Italy

DOI:

https://doi.org/10.51273/esc24.251320224

Abstract

Objective: The objective of this descriptive study was to investigate the age distribution, gender prevalence,
clinical presentations, histological patterns, tumor staging, and outcomes of WT in a local pediatric population.
Material and Methods: The study conducted over 9 months at Children Hospital, Lahore. The study included
120 patients with WT. Clinical data, age, gender, and staging information were collected. Biopsies were
analyzed for histological patterns, and SPSS version 26 was used for statistical analysis.
Results: The study revealed a mean age of 5.79 years, with a slight male predominance (58.3%). Abdominal
mass was the predominant clinical presentation (47.5%), and the tri-phasic histological pattern, often with blastemal predominance, was most prevalent (52.5%). The majority of cases were diagnosed at Stage-I (59.2%). No significant associations were found between age, gender, and tumor subtypes.
Conclusion: The findings reveal a predominance of the tri-phasic histological pattern with blastemal predominance, aligning with global trends.

Author Biographies

Bushra Nisar, Children Hospital Lahore

Assistant professor Histopathology

Saadia Sharif, The University of Lahore-Pakistan

Associate professor

Abeer Zaheer, Children Hospital Lahore

Assistant professor Histopathology

Samina Zaman, Children Hospital Lahore

Professor Histopathology

Mehwish Hussain, Children Hospital Lahore

Associate professor Histopathology

Zunaira Jamshed, Fatima memorial Hospital Lahore

Medical Student

Tayyaba Yasin, The University of Campania Luigi Vanvitelli, Italy

PhD student

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Published

2024-07-18

How to Cite

1.
Bushra Nisar, Saadia Sharif, Abeer Zaheer, Samina Zaman, Mehwish Hussain, Zunaira Jamshed, Yasin T. Wilms Tumor Different Histology Patterns Observed in Tertiary Care Hospital. Esculapio - JSIMS [Internet]. 2024 Jul. 18 [cited 2024 Dec. 21];20(2). Available from: https://esculapio.pk/journal/index.php/journal-files/article/view/1057

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Original Articles